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View industry Manufacturing Update operations, upskill your workforce, and transform your business with manufacturing solutions from Sysdoc. View industry Technology and Telecommunications Collaborating with you to implement the knowledge and tools required for success. View industry Solutions We are known for delivering successful outcomes in these technologies and functional areas time and time again. AI Products and Services Sysdoc can help your business start its AI journey, identify initial AI opportunities, and deliver immediate value. With four decades of experience in adapting to new technologies, we ensure successful AI implementation. View solution Microsoft 365 Adoption Helping your organisation maximise the benefit of Microsoft 365 faster. View solution SAP S\u002F4HANA Our SAP S\u002F4HANA implementation support helps you maximise the value of this world-class ERP application. View solution Oracle JD Edwards and Cloud Supporting your Oracle implementations to optimise operations and achieve operational excellence. View solution Salesforce Supporting Salesforce integration projects from the ground up. View solution Procurement Delivering change, adoption, process and knowledge services to organisations seeking to transform the way they procure and source. View solution Environment, Health and Safety Creating robust resources for Environment, Health and Safety. View solution Human Resources Helping you optimise your People Services, meet your commitments to your employees and deliver strategic Human Resources (HR) outcomes through the transformation of your organisation, capabilities, behaviours, systems and processes. View solution Latest Case Studies See all case studies [ MyWave • Technology and Telecommunications Project Management & Operating Model Enablement for a Fast-Growing Agentic AI Organisation Discover how Sysdoc helped a fast growing AI company scale its operations through embedded project management, process design, and roadmap governance. ](\u002Fnz\u002Fcase-studies\u002Fproject-management-operating-model-enablement-for-a-fast-growing-agentic-ai-organisation)Learn more [ Tower Insurance • Financial Services Transforming Operational Capability Through Uplifting Process Discover how Sysdoc helped Tower transform operations with end‑to‑end process mapping, governance, and rapid BPM implementation to enable AI‑ready performance. ](\u002Fnz\u002Fcase-studies\u002Ftransforming-operational-capability-through-uplifting-process)Learn more [ ![](https:\u002F\u002Fcdn.prod.website-files.com …",true,1,"1",{"id":354,"height":13,"width":12,"blurhash":355},"60087354-9f3b-49df-9587-5564eb44f411","radial-gradient(at 0 0,#343445,#00000000 50%),radial-gradient(at 33% 0,#2b3e4c,#00000000 50%),radial-gradient(at 67% 0,#373e4a,#00000000 50%),radial-gradient(at 100% 0,#3c484f,#00000000 50%),radial-gradient(at 0 50%,#56666d,#00000000 50%),radial-gradient(at 33% 50%,#4b5864,#00000000 50%),radial-gradient(at 67% 50%,#5d646b,#00000000 50%),radial-gradient(at 100% 50%,#5c6266,#00000000 50%),radial-gradient(at 0 100%,#000027,#00000000 50%),radial-gradient(at 33% 100%,#153c4f,#00000000 50%),radial-gradient(at 67% 100%,#4a565e,#00000000 50%),radial-gradient(at 100% 100%,#46494c,#00000000 50%)",{"id":357,"height":15,"width":14,"blurhash":52},"30a2e2e5-5b87-45d3-b038-1365878c5af6",[359,362,365,368,371,374,377,380,383,386,389,392,395,398,401,404,407,410,413,416,419,422,425,428,431,434,437,440,443,446],{"directus_files_id":360},{"id":361},"83931dbb-c856-4624-ade4-9e17ae28eb83",{"directus_files_id":363},{"id":364},"113e605f-8d0d-47ff-a5b1-6bc6469d8873",{"directus_files_id":366},{"id":367},"3c3fd087-56ed-4b35-af8c-0cfdf4d1c90f",{"directus_files_id":369},{"id":370},"cd46a555-f22e-4d64-93ce-9bfc7e700113",{"directus_files_id":372},{"id":373},"c4ff8d67-f9a6-4cdc-accf-4c9c5ef393da",{"directus_files_id":375},{"id":376},"d9a2b8e8-079c-41b9-9bd0-58d3c69f8eb3",{"directus_files_id":378},{"id":379},"bc5bb2a2-f8f0-4772-b623-f815bfe44335",{"directus_files_id":381},{"id":382},"667b4fcc-d04a-41c0-9d71-09de2191f7e0",{"directus_files_id":384},{"id":385},"c29f08ff-2368-4087-8922-4881511eb15f",{"directus_files_id":387},{"id":388},"b10a0c49-a2bf-41d3-ae1e-77990679f465",{"directus_files_id":390},{"id":391},"895a2dc7-e2d9-49d3-9618-4e566497c990",{"directus_files_id":393},{"id":394},"1671cf64-3239-4545-aae8-412ac3f79670",{"directus_files_id":396},{"id":397},"5f1e2c12-c497-4998-ad08-a3cd41b4ee13",{"directus_files_id":399},{"id":400},"4eede706-37a3-44e7-87f9-fe0eb2a28830",{"directus_files_id":402},{"id":403},"6f1b796c-5a0b-434b-870d-97ee0b9cc24d",{"directus_files_id":405},{"id":406},"c4d8a60f-ff02-47cf-9bcf-fa4c106bfe6e",{"directus_files_id":408},{"id":409},"c2093591-6622-45d0-aec2-71a45bbdca1f",{"directus_files_id":411},{"id":412},"d242b335-4df3-4e3b-8143-219c5bc47445",{"directus_files_id":414},{"id":415},"ecc7d8d2-8231-4031-b04f-3bf2ff304e9f",{"directus_files_id":417},{"id":418},"16a8921a-986c-4c37-a73d-e017fb1b205a",{"directus_files_id":420},{"id":421},"ba884f1f-5ea0-44a0-87c9-53ca53739f34",{"directus_files_id":423},{"id":424},"9f127fbb-239a-4a92-aaa1-4a31b697576d",{"directus_files_id":426},{"id":427},"edde199f-ba2a-46bb-a385-923219971a61",{"directus_files_id":429},{"id":430},"2df6440f-c223-426d-845c-2a702da4657d",{"directus_files_id":432},{"id":433},"cf4a5e5b-e4ec-4819-83b0-595183b36a33",{"directus_files_id":435},{"id":436},"bb593fe1-9479-4a37-b484-977d4eaa76a3",{"directus_files_id":438},{"id":439},"50deedd5-fb0a-47ec-94b4-7524005432e2",{"directus_files_id":441},{"id":442},"f8b91417-986b-49b9-86a0-a295afc0c3b8",{"directus_files_id":444},{"id":445},"8174be29-eb39-48bd-8aec-e15097bd1bc5",{"directus_files_id":447},{"id":448},"d2256b55-b9a1-41d1-9ab6-ffb883796451",[450],{"languages_code":451,"description":452},"en","Sysdoc is a strategic consultancy dedicated to driving business transformation, learning innovation, and digital experience. The website serves as a professional gateway for organizations seeking to modernize their operations through a people-first approach, emphasizing smarter, more efficient ways of working. Through a blend of case studies, insights, and service overviews, the platform establishes Sysdoc as a thought leader in navigating complex organizational shifts.\n\nThe visual identity is sophisticated and modern, utilizing a deep, dark-mode aesthetic paired with high-contrast typography. The use of bold, sans-serif headings and a vibrant teal accent color creates a sense of energy and forward momentum. High-quality, atmospheric photography adds a human element to the corporate messaging, ensuring the brand feels approachable yet authoritative. The clean layout and spacious design reflect the brand's core promise of making business processes 'simpler' and 'smarter.'","Agency & Studio",[29,455,26],"Corporate \u002F Professional",[],[306,306],[76,88,281],[460,462,463,464],{"score":461,"category":92},63,{"score":193,"category":95},{"score":153,"category":98},{"score":192,"category":101},[466,468,469,470],{"score":467,"category":92},52,{"score":206,"category":95},{"score":200,"category":98},{"score":192,"category":101},[115,119,111],"Website: Sysdoc. Page: Homepage. Page type: Home \u002F Landing Page. Page title: Sysdoc - Business Transformation, Learning Innovation and Digital Experience. Page description: Sysdoc is about business transformation, innovation and growth – simpler, smarter ways of working in your organisation.. Page content: Opens in a new window Opens an external website Opens an external website in a new window This website utilizes technologies such as cookies to enable essential site functionality, as well as for analytics, personalization, and targeted advertising purposes. To learn more, view the following link: Privacy Policy Sysdoc Logo Sysdoc Services Services All ServicesBusiness TransformationLearning InnovationDigital ExperienceProducts and ToolsWorkshops and EventsDiscovery WorkshopAI Discovery WorkshopAI Catalogue Industries AgribusinessPublic SectorFinancial ServicesDefenceInfrastructure and ConstructionMaritimeManufacturingTechnology and Telecommunications Solutions Artificial Intelligence (AI)SAP S\u002F4HANAOracle JDESalesforceMicrosoft 365ProcurementEnvironment, Health and SafetyHuman Resources Approach Story Case Studies Insights and News People Serendata  NZ NZ UK Contact Simpler, smarter working Adapt, innovate, and accelerate your business with our people-first approach to business transformation. Who we are We are a global consultancy and recognised business leader in business transformation, learning and innovative technology. Discover our approach [ Services ](#w-tabs-0-data-w-pane-0)[ Industries ](#w-tabs-0-data-w-pane-1)[ Solutions ](#w-tabs-0-data-w-pane-2) Our Services With a wide range of services based around business transformation, learning innovation and digital experience, we combine elements to create a custom solution for your organisation. View all servicesProducts and tools Business Transformation [ Get ready for AI: Business Process ](\u002Fnz\u002Fservice-components\u002Fget-ready-for-ai-business-process) [ Get ready for AI: Data ](\u002Fnz\u002Fservice-components\u002Fget-ready-for-ai-data) [ Business Process Design and Improvement ](\u002Fnz\u002Fservice-components\u002Fbusiness-process-design-and-improvement) [ Change Management ](\u002Fnz\u002Fservice-components\u002Fchange-management) [ Information Management ](\u002Fnz\u002Fservice-components\u002Finformation-management) [ Organisation Design ](\u002Fnz\u002Fservice-components\u002Forganisation-design) [ Project and Programme Management ](\u002Fnz\u002Fservice-components\u002Fproject-programme-management) [ Culture Change ](\u002Fnz\u002Fservice-components\u002Fculture-change) [ Operating Model Design ](\u002Fnz\u002Fservice-components\u002Foperating-model-design) [ Technical Writing and Documentation ](\u002Fnz\u002Fservice-components\u002Ftechnical-writing-aka-documentation) View service Learning Innovation [ Learning Technologies Review ](\u002Fnz\u002Fservice-components\u002Flearning-technologies-review) [ AI Adoption ](\u002Fnz\u002Fservice-components\u002Fai-adoption) [ Blended Learning Programmes ](\u002Fnz\u002Fservice-components\u002Fblended-learning-programmes) [ System and Process Learning ](\u002Fnz\u002Fservice-components\u002Fsystem-and-process-training) [ Instructor-led Learning ](\u002Fnz\u002Fservice-components\u002Finstructor-led-learning) [ Digital Learning ](\u002Fnz\u002Fservice-components\u002Fdigital-learning) [ Game-based Learning ](\u002Fnz\u002Fservice-components\u002Fgame-based-learning) [ Leadership and Teamwork Training ](\u002Fnz\u002Fservice-components\u002Fleadership-and-teamwork-training) [ Learning Strategy and Design ](\u002Fnz\u002Fservice-components\u002Flearning-strategy-and-design) View service Digital Experience [ Knowledge Management ](\u002Fnz\u002Fservice-components\u002Fknowledge-management) [ User Experience and Design ](\u002Fnz\u002Fservice-components\u002Fuser-experience-and-design) [ Video Production ](\u002Fnz\u002Fservice-components\u002Fvideo-production) [ SharePoint Development and Productivity Tools ](\u002Fnz\u002Fservice-components\u002Fsharepoint-development-and-productivity-tools) [ Power BI Data Visualisation and Intelligence ](\u002Fnz\u002Fservice-components\u002Fpower-bi-data-visualisation-and-intelligence) [ Custom AI Development ](\u002Fnz\u002Fservice-components\u002Fai-agent-development) View service Industries We have delivered quality outcomes across a wide range of public and private sectors since 1986. Agribusiness Supporting the rapidly changing Agribusiness sector with our learning design, process excellence, knowledge management and change management expertise with our purpose-built tools. View industry Public Sector Delivering the people side of public sector transformation, from clear strategic pathways and simpler ways of working, to process improvement and innovative learning. View industry Financial Services Supporting financial services organisations through complex transformation, regulatory change and evolving customer expectations. View industry Defence Empowering Defence agencies to lift performance and transform. View industry Infrastructure and Construction Driving transformation for infrastructure and construction organisations in a highly competitive global marketplace. View industry Maritime Sysdoc is a leader in driving digital transformation and enhancing operational efficiency within the maritime sector. View industry Manufacturing Update operations, upskill your workforce, and transform your business with manufacturing solutions from Sysdoc. View industry Technology and Telecommunications Collaborating with you to implement the knowledge and tools required for success. View industry Solutions We are known for delivering successful outcomes in these technologies and functional areas time and time again. AI Products and Services Sysdoc can help your business start its AI journey, identify initial AI opportunities, and deliver immediate value. With four decades of experience in adapting to new technologies, we ensure successful AI implementation. View solution Microsoft 365 Adoption Helping your organisation maximise the benefit of Microsoft 365 faster. View solution SAP S\u002F4HANA Our SAP S\u002F4HANA implementation support helps you maximise the value of this world-class ERP application. View solution Oracle JD Edwards and Cloud Supporting your Oracle implementations to optimise operations and achieve operational excellence. View solution Salesforce Supporting Salesforce integration projects from the ground up. View solution Procurement Delivering change, adoption, process and knowledge services to organisations seeking to transform the way they procure and source. View solution Environment, Health and Safety Creating robust resources for Environment, Health and Safety. View solution Human Resources Helping you optimise your People Services, meet your commitments to your employees and deliver strategic Human Resources (HR) outcomes through the transformation of your organisation, capabilities, behaviours, systems and processes. View solution Latest Case Studies See all case studies [ MyWave • Technology and Telecommunications Project Management & Operating Model Enablement for a Fast-Growing Agentic AI Organisation Discover how Sysdoc helped a fast growing AI company scale its operations through embedded project management, process design, and roadmap governance. ](\u002Fnz\u002Fcase-studies\u002Fproject-management-operating-model-enablement-for-a-fast-growing-agentic-ai-organisation)Learn more [ Tower Insurance • Financial Services Transforming Operational Capability Through Uplifting Process Discover how Sysdoc helped Tower transform operations with end‑to‑end process mapping, governance, and rapid BPM implementation to enable AI‑ready performance. ](\u002Fnz\u002Fcase-studies\u002Ftransforming-operational-capability-through-uplifting-process)Learn more [ ![](https:\u002F\u002Fcdn.prod.website-files.com …. A Clean \u002F Minimalist, Corporate \u002F Professional, Dark Mode website in the Agency & Studio industry. The overall color palette features White, Gray, Black. The typography features Lato (Sans Serif), Lato (Sans Serif). Built using Google Font API, jQuery, Typekit. AI description: Sysdoc is a strategic consultancy dedicated to driving business transformation, learning innovation, and digital experience. The website serves as a professional gateway for organizations seeking to modernize their operations through a people-first approach, emphasizing smarter, more efficient ways of working. Through a blend of case studies, insights, and service overviews, the platform establishes Sysdoc as a thought leader in navigating complex organizational shifts. The visual identity is sophisticated and modern, utilizing a deep, dark-mode aesthetic paired with high-contrast typography. The use of bold, sans-serif headings and a vibrant teal accent color creates a sense of energy and forward momentum. High-quality, atmospheric photography adds a human element to the corporate messaging, ensuring the brand feels approachable yet authoritative. 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Leverage AI to generate protein candidates and improve their properties. More breakthroughs in fewer experiments — guided by your own experimental data.","[ ](.\u002F) Platform Solutions Company Licensing Resources [ Sign in ](https:\u002F\u002Fapp.cradle.bio\u002Flogin) [ Talk to sales ](.\u002Fget-started) [ News: Introducing CRADLE-1 whitepaper ](.\u002Fwhitepaper) Leverage AI to generate protein candidates and improve their properties. More breakthroughs in fewer experiments — guided by your own experimental data. data ui round ui report ui Generate candidates Track round status easily, from generating candidates to uploading experimental results. Explore reports Manage data OUR CUSTOMERS Trusted by the world's top Biopharma and Industrial Bio R&D teams Through our partnership with Cradle, we are embedding advanced Al directly into how we innovate, enabling our teams to shorten development time and bring real-world biosolutions faster to market. Claus Fuglsang Crone Chief Scientific Officer, Novonesis [ customer-logo Read announcement ](https:\u002F\u002Fwww.linkedin.com\u002Fposts\u002Fnovonesis_biosolutions-innovation-collaboration-activity-7407400799586189312-edTX\u002F)[ customer-logo Read article ](https:\u002F\u002Fwww.pharmavoice.com\u002Fnews\u002Fai-drug-discovery-pharma-immunai-pfizer-novo-nordisk-cradle\u002F758994\u002F) customer-logo [ customer-logo Read announcement ](https:\u002F\u002Fwww.cradle.bio\u002Fblog\u002Fbayer-collaboration) customer-logo customer-logo customer-logo customer-logo customer-logo customer-logo customer-logo Recent case studies [ Using AI to produce vaccine adjuvants without cutting down rainforest ](.\u002Fblog\u002Fkeasling-qs21)[ Engineering therapeutic peptides with 50% success rate under tight multi-property constraints, 5× faster than prior efforts ](.\u002Fblog\u002Ftherapeutic-peptides)[ Improving Staphylococcus aureus vaccine thermostability by 2.5 °C in a single round, 7× faster than rational design ](.\u002Fblog\u002Fstaphylococcus-aureus-vaccine) PROTEIN ENGINEERING 2.0 Compounding results across all properties Get products to market in quarters, not years. Use Cradle to chart the fastest course to proteins that meet all your desired objectives. Explore further, optimize faster, and reach your destination in fewer experiments. +300% T7 RNA Abstract image of clustered white circles on a dark teal background. 1 2 3 4 Round Progress with Cradle Compounding results Move from incremental progress to compounding results with models that learn from every round of your wet lab data. Teams that use Cradle report 2-12x faster development timelines. Breakthroughs on repeat Following a single path puts you at risk of hitting a dead end. Instead, confidently explore multiple design strategies to bring more programs over the finish line and strengthen your IP portfolio. All projects mAb-HER2 Round 4 mAb-TNF Completed vax-HPV9 Completed Binding affinity Specificity Activity Stability Expression Co-optimize all your properties Activity, binding, stability, expression, and more. Co-optimize the properties you care about, turning complex trade-offs into optimized solutions in fewer rounds. WORK ON ANY PROTEIN Built for any protein and all properties Accelerate your journey from hit identification to lead optimization and beyond. If you can measure it, you can optimize it with Cradle. This makes Cradle fit-for-purpose for teams developing therapeutics, agricultural solutions, food ingredients, and more. Antibodies Craft mature and developable binders that avoid unwanted immunogenicity. Enzymes Accelerate specific catalytic conversions, even in challenging conditions. Vaccines Stabilize your antigens and hit therapeutic goals faster. Peptides Get to desired efficacy while ensuring stability. HOW CRADLE WORKS Design in Cradle. Validate in the lab. Quickly generate lab-ready protein candidates to test in your own lab or with a CRO. Track model and candidate performance in your reports. Learn every time you add assay data. [ Explore platform ](.\u002Fplatform) Validate in the lab 4 Build 5 Test 6 Upload Design in Cradle 1 Learn 2 Generate 3 Review Learn 1 Import your data To begin, upload wet lab data from screening or optimization experiments. If you're starting a project from scratch, simply define your goals and assays to get going. Explore your data quality Cradle automatically analyses your experimental data to determine data quality and AI’s ability to learn from it. This helps you to understand how to improve your workflows and assays to get to optimal sequences faster. Models learn with you Every time you upload lab results, Cradle gets better at understanding your protein. This means increasingly performant variants that get you closer to your goals— every round. Generate 2 Generate candidates The game-changer of Cradle: new, optimized candidates at the click of a button. Choose a design strategy, set sequence- or lab based constraints, bring in your knowledge of the protein and hit ‘Generate’. No PhD in computer science needed. Multi-property support Cradle learns the complex interactions between all properties of your protein. During generation, this translates into candidates that balance improved performance across properties with high scores on diversity and novelty. Full-plate optimization The sequences that you download from Cradle are a carefully curated set, selected from millions of _in silico_ designs to maximize your chances of success. Review 3 Reports Generation Reports give you full control over what candidates you bring to the lab and what to expect in performance. See predictive performance scores for your entire plate and explore specific sequences and mutations in 3D. Send to lab Now it’s time to turn bits into atoms. Download sequences from Cradle, then order DNA and run assays in your own lab. Or send the sequences to your favorite CRO. Round statuses Track lab progress in Cradle using Round Statuses and see live metrics per protein property as new assay data comes in from testing. PRIVATE. SECURE. YOURS With Cradle, your sequences and data remain private, secure, and entirely yours. Only you and those you invite can access your data, which is never used to train models for others. Protected by bank-grade security, your data stays secure at all times. Plus, you retain full ownership of your intellectual property—no royalties, just a software subscription fee. Privacy-first AI You experimental data is only used to train your organizations custom models. SOC 2 compliant Cradle is fully SOC 2 compliant with active monitoring and tight security protocols in place. Single Sign-on Secure and simple account management with SSO support for Google and Microsoft. Custom predictors BETA Use internally developed predictors right in Cradle and see outputs inside Reports. Zero-maintenance Fully managed AI infrastructure with optimized GPU that scales with your need. Dedicated support Our team of scientists and ML experts are ready to assist with any issues. THE CRADLE LAB AI that gets better every two weeks Cradle isn’t a CRO, so why do we run our own wet lab in Amsterdam? It's simple. So you get reliable and high-performing models from day one, while your proprietary data remains completely private. Much like a self-driving car company: they wouldn’t just design algorithms and cross their fingers. They need to test real-world scenarios and collect data in order to fine-tune performance. We take the same approach, ensuring our models are performant even before seeing your data. 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By integrating experimental data with generative AI, the platform enables scientists to design, optimize, and validate protein candidates with unprecedented speed and precision. It serves as a critical bridge between computational modeling and wet-lab validation, aiming to reduce the number of physical experiments required to achieve breakthrough biological results.\n\nThe visual identity is deeply rooted in a high-tech, scientific aesthetic, utilizing a sleek dark mode interface that conveys authority and cutting-edge innovation. The design employs bold, oversized typography to command attention, paired with a clean, structured layout that mirrors the precision of the laboratory. Through a combination of minimalist UI elements and high-contrast visual hierarchy, the website establishes a professional and futuristic tone that resonates with a highly specialized audience of researchers, biotech engineers, and pharmaceutical innovators.","SaaS & Software",[29,26,588],"Futuristic \u002F Sci-Fi",[],[591,295,592],"Spot Mono","JetBrains Mono",[290,274],[595,596,597,598],{"score":193,"category":92},{"score":193,"category":95},{"score":343,"category":98},{"score":192,"category":101},[600,601,602,603],{"score":199,"category":92},{"score":223,"category":95},{"score":343,"category":98},{"score":192,"category":101},[111,115,605,119],"violet","Website: Cradle. Page: Homepage. Page type: Home \u002F Landing Page. Page title: Cradle | Engineer better proteins, faster.. Page description: Protein engineering AI, built for scientists. Leverage AI to generate protein candidates and improve their properties. More breakthroughs in fewer experiments — guided by your own experimental data.. Page content: [ ](.\u002F) Platform Solutions Company Licensing Resources [ Sign in ](https:\u002F\u002Fapp.cradle.bio\u002Flogin) [ Talk to sales ](.\u002Fget-started) [ News: Introducing CRADLE-1 whitepaper ](.\u002Fwhitepaper) Leverage AI to generate protein candidates and improve their properties. More breakthroughs in fewer experiments — guided by your own experimental data. data ui round ui report ui Generate candidates Track round status easily, from generating candidates to uploading experimental results. Explore reports Manage data OUR CUSTOMERS Trusted by the world's top Biopharma and Industrial Bio R&D teams Through our partnership with Cradle, we are embedding advanced Al directly into how we innovate, enabling our teams to shorten development time and bring real-world biosolutions faster to market. Claus Fuglsang Crone Chief Scientific Officer, Novonesis [ customer-logo Read announcement ](https:\u002F\u002Fwww.linkedin.com\u002Fposts\u002Fnovonesis_biosolutions-innovation-collaboration-activity-7407400799586189312-edTX\u002F)[ customer-logo Read article ](https:\u002F\u002Fwww.pharmavoice.com\u002Fnews\u002Fai-drug-discovery-pharma-immunai-pfizer-novo-nordisk-cradle\u002F758994\u002F) customer-logo [ customer-logo Read announcement ](https:\u002F\u002Fwww.cradle.bio\u002Fblog\u002Fbayer-collaboration) customer-logo customer-logo customer-logo customer-logo customer-logo customer-logo customer-logo Recent case studies [ Using AI to produce vaccine adjuvants without cutting down rainforest ](.\u002Fblog\u002Fkeasling-qs21)[ Engineering therapeutic peptides with 50% success rate under tight multi-property constraints, 5× faster than prior efforts ](.\u002Fblog\u002Ftherapeutic-peptides)[ Improving Staphylococcus aureus vaccine thermostability by 2.5 °C in a single round, 7× faster than rational design ](.\u002Fblog\u002Fstaphylococcus-aureus-vaccine) PROTEIN ENGINEERING 2.0 Compounding results across all properties Get products to market in quarters, not years. Use Cradle to chart the fastest course to proteins that meet all your desired objectives. Explore further, optimize faster, and reach your destination in fewer experiments. +300% T7 RNA Abstract image of clustered white circles on a dark teal background. 1 2 3 4 Round Progress with Cradle Compounding results Move from incremental progress to compounding results with models that learn from every round of your wet lab data. Teams that use Cradle report 2-12x faster development timelines. Breakthroughs on repeat Following a single path puts you at risk of hitting a dead end. Instead, confidently explore multiple design strategies to bring more programs over the finish line and strengthen your IP portfolio. All projects mAb-HER2 Round 4 mAb-TNF Completed vax-HPV9 Completed Binding affinity Specificity Activity Stability Expression Co-optimize all your properties Activity, binding, stability, expression, and more. Co-optimize the properties you care about, turning complex trade-offs into optimized solutions in fewer rounds. WORK ON ANY PROTEIN Built for any protein and all properties Accelerate your journey from hit identification to lead optimization and beyond. If you can measure it, you can optimize it with Cradle. This makes Cradle fit-for-purpose for teams developing therapeutics, agricultural solutions, food ingredients, and more. Antibodies Craft mature and developable binders that avoid unwanted immunogenicity. Enzymes Accelerate specific catalytic conversions, even in challenging conditions. Vaccines Stabilize your antigens and hit therapeutic goals faster. Peptides Get to desired efficacy while ensuring stability. HOW CRADLE WORKS Design in Cradle. Validate in the lab. Quickly generate lab-ready protein candidates to test in your own lab or with a CRO. Track model and candidate performance in your reports. Learn every time you add assay data. [ Explore platform ](.\u002Fplatform) Validate in the lab 4 Build 5 Test 6 Upload Design in Cradle 1 Learn 2 Generate 3 Review Learn 1 Import your data To begin, upload wet lab data from screening or optimization experiments. If you're starting a project from scratch, simply define your goals and assays to get going. Explore your data quality Cradle automatically analyses your experimental data to determine data quality and AI’s ability to learn from it. This helps you to understand how to improve your workflows and assays to get to optimal sequences faster. Models learn with you Every time you upload lab results, Cradle gets better at understanding your protein. This means increasingly performant variants that get you closer to your goals— every round. Generate 2 Generate candidates The game-changer of Cradle: new, optimized candidates at the click of a button. Choose a design strategy, set sequence- or lab based constraints, bring in your knowledge of the protein and hit ‘Generate’. No PhD in computer science needed. Multi-property support Cradle learns the complex interactions between all properties of your protein. During generation, this translates into candidates that balance improved performance across properties with high scores on diversity and novelty. Full-plate optimization The sequences that you download from Cradle are a carefully curated set, selected from millions of _in silico_ designs to maximize your chances of success. Review 3 Reports Generation Reports give you full control over what candidates you bring to the lab and what to expect in performance. See predictive performance scores for your entire plate and explore specific sequences and mutations in 3D. Send to lab Now it’s time to turn bits into atoms. Download sequences from Cradle, then order DNA and run assays in your own lab. Or send the sequences to your favorite CRO. Round statuses Track lab progress in Cradle using Round Statuses and see live metrics per protein property as new assay data comes in from testing. PRIVATE. SECURE. YOURS With Cradle, your sequences and data remain private, secure, and entirely yours. Only you and those you invite can access your data, which is never used to train models for others. Protected by bank-grade security, your data stays secure at all times. Plus, you retain full ownership of your intellectual property—no royalties, just a software subscription fee. Privacy-first AI You experimental data is only used to train your organizations custom models. SOC 2 compliant Cradle is fully SOC 2 compliant with active monitoring and tight security protocols in place. Single Sign-on Secure and simple account management with SSO support for Google and Microsoft. Custom predictors BETA Use internally developed predictors right in Cradle and see outputs inside Reports. Zero-maintenance Fully managed AI infrastructure with optimized GPU that scales with your need. Dedicated support Our team of scientists and ML experts are ready to assist with any issues. THE CRADLE LAB AI that gets better every two weeks Cradle isn’t a CRO, so why do we run our own wet lab in Amsterdam? It's simple. So you get reliable and high-performing models from day one, while your proprietary data remains completely private. Much like a self-driving car company: they wouldn’t just design algorithms and cross their fingers. They need to test real-world scenarios and collect data in order to fine-tune performance. We take the same approach, ensuring our models are performant even before seeing your data. [ Get to know our wet lab ](.\u002Flab) Learnings from our wet lab [ ![](https:\u002F\u002Fframerusercontent.com\u002Fimages\u002FbGwzodiFTanxuEUdEmGVycl1E.png?width=1200&heig …. A Clean \u002F Minimalist, Dark Mode, Futuristic \u002F Sci-Fi website in the SaaS & Software industry. The overall color palette features Black, White, Violet, Gray. The typography features Spot Mono (Sans Serif, Schick Toikka), Inter (Sans Serif), JetBrains Mono (Sans Serif). Built using Framer Sites, React. AI description: Cradle is a sophisticated biotechnology platform designed to accelerate protein engineering through the power of artificial intelligence. By integrating experimental data with generative AI, the platform enables scientists to design, optimize, and validate protein candidates with unprecedented speed and precision. It serves as a critical bridge between computational modeling and wet-lab validation, aiming to reduce the number of physical experiments required to achieve breakthrough biological results. The visual identity is deeply rooted in a high-tech, scientific aesthetic, utilizing a sleek dark mode interface that conveys authority and cutting-edge innovation. 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The only offline-first database with built-in peer-to-peer networking Schedule a demoSchedule a demo Schedule a demo Try Ditto for freeTry Ditto for free Try Ditto for free Building an LLM Wiki for Ditto: How a Mac Mini Became My Second BrainBuilding an LLM Wiki for Ditto: How a Mac Mini Became My Second Brain Blog Building an LLM Wiki for Ditto: How a Mac Mini Became My Second Brain We Built a Browser Robot Because Webflow's API Can't Handle a Code BlockWe Built a Browser Robot Because Webflow's API Can't Handle a Code Block Blog We Built a Browser Robot Because Webflow's API Can't Handle a Code Block Build a Multiplayer Emoji Game in SwiftUI with Peer-to-Peer SyncBuild a Multiplayer Emoji Game in SwiftUI with Peer-to-Peer Sync Blog Build a Multiplayer Emoji Game in SwiftUI with Peer-to-Peer Sync Keep mission-critical systems online when it matters most Ditto is the only edge-native, mobile database that can consistently support your business anytime, anywhere. Edge-native solutions are built specifically to thrive on mobile and edge devices, without relying solely on cloud-based services. - Build flexible operations that are both latency-sensitive and resilient without reliance on network hardware, edge servers, or the cloud - Decentralize your systems to remove single points of failure that lead to operational bottlenecks - Drive consistent revenue and customer service anywhere, regardless of connectivity or bandwidth Try Ditto for FreeTry Ditto for Free Try Ditto for Free Meet with a Product SpecialistMeet with a Product Specialist Meet with a Product Specialist “When your POS goes down, that has a true financial cost to your business” Once Ditto is installed in your applications, write a few simple queries, and watch your mobile and edge devices automatically form mesh networks and share data directly without the need for servers or access points. Hear the full storyHear the full story Hear the full story See more customersSee more customers See more customers [The Ditto MongoDB Connector - Setup and Demo ](#) The Tech Take a quick look at the core technology powering our peer-to-peer and cloud sync plans. Foundational Technology Offline-first mobile database Even when devices are completely offline, they can always read, write, and process data Offline-first mobile database CRDT-powered conflict resolution To resolve concurrency conflicts that appear in decentralized models, as well as enable delta-based sync, Ditto harnesses the power of conflict-free replicated data type (CRDT) technology CRDT-powered conflict resolution [ P2P Sync ](#w-tabs-0-data-w-pane-0)[ Device Sync ](#w-tabs-0-data-w-pane-1) Automatic Device Discovery and Mesh Networking Devices running the same application automatically connect and maintain ad-hoc mesh networks without the need for manual pairing or configuration ![Automatic Device Discovery and Mesh Networking](https:\u002F\u002Fcdn.prod.website-files.com\u002F6761335affb7c1ca9aae00dd\u002F6797603559859902bdfdf85f_ditto_home-tech_visual_003@2x.webp) Direct Peer-to-Peer Sync Out-of-the-box support for BLE, P2P WiFi, LAN, and more enables real-time sync in disconnected or bandwidth-constrained environments Direct Peer-to-Peer Sync Opportunistic Cloud Sync Anytime internet is available to one or more devices within the mesh, all devices sync with your existing cloud systems Opportunistic Cloud Sync Opportunistic Cloud Sync Anytime internet is available, devices sync with your existing cloud systems Opportunistic Cloud Sync Success Stories See more customersSee more customers See more customers Vikram Baskaran “Our Ditto partnership is providing real-time visibility for inflight devices” \"Our approach to developing frontline tools prioritizes close partnership with our flight attendants during each development step. Ditto has been a great partner in ensuring our tools are seamless for our flight attendants. With their help, we have supported our workgroup by providing visibility of one another’s inflight mobile device… in real-time\" Read More Vikram BaskaranVP of IT Alaska Airlines Chris Taylor “Ditto moves key data quickly with no round trips to central services” “Ditto moves key operational data between retail team members quickly, seamlessly and with no round trips to central services. The more control and information we can put in the hands of operators and their teams, the better they can care for customers.” Read More Chris TaylorRetail Ops Manager Chick-fil-a Ms. Yu Abe “This technology truly revolutionizes the way crew members work” Ditto's remarkable capabilities enable smooth and stable communication among crew devices, even without connectivity during flight. This allows our crew to shift from former manual operations to a more advanced and efficient working style and enables us to create more room for the crew to introduce new services to passengers. This technology truly revolutionizes the way crew members work. Read More Ms. Yu AbeDirector, IT Planning & Promotion Department Japan Airlines Bryan Allebone “Ditto ensures USAF's data remains as reliably agile as we are” Ditto is our strategy to ensure that USAF's data remains as reliably agile as we are… with Ditto, married with these Apple Platforms… we can provide a seamless and mission-ready experience anywhere in the world, and under any circumstances. Read More Bryan AlleboneMajor 55th Wing \u002F BOCKSCAR U.S. Air Force Harness the full power of your existing mobile and edge infrastructure More WiFi isn’t the answer. Your mobile and edge devices are more powerful than you realize, capable of advanced networking without the need for new devices, hardware, or networking setups. Bridge connectivity gaps without added hardware or complexity. Once Ditto is installed in your applications, write a few simple queries, and watch your mobile and edge devices automatically form mesh networks and share data directly without the need for servers or access points. 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By leveraging peer-to-peer networking, the platform allows devices to communicate and sync data without the constant need for centralized servers or cloud infrastructure, making it an essential tool for mission-critical applications in disconnected environments.\n\nThe visual identity is strikingly modern and high-tech, utilizing a clean, minimalist aesthetic characterized by expansive white space and bold, oversized typography. The use of a subtle dot-grid background adds a technical, engineering-focused texture that appeals to developers and enterprise architects. The design strikes a perfect balance between professional reliability and cutting-edge innovation, signaling a premium SaaS solution for complex infrastructure challenges.",[29,33],[723],"Sam Dallyn",[295,725],"Aeonik Fono",[76,727,728,88],"Highlight.js","HubSpot Chat",[730,732,733,734],{"score":731,"category":92},53,{"score":206,"category":95},{"score":343,"category":98},{"score":192,"category":101},[736,737,738,739],{"score":154,"category":92},{"score":615,"category":95},{"score":343,"category":98},{"score":192,"category":101},[115,111,119,741],"yellow","Website: Ditto. Page: Homepage. Page type: Home \u002F Landing Page. Page title: Ditto - Resilient Edge Device Connectivity. Page description: The only mobile database with built-in edge device connectivity and resiliency. Page content: ResilientEdgeDeviceConnectivity.Servers&Cloud Optional. The only offline-first database with built-in peer-to-peer networking Schedule a demoSchedule a demo Schedule a demo Try Ditto for freeTry Ditto for free Try Ditto for free Building an LLM Wiki for Ditto: How a Mac Mini Became My Second BrainBuilding an LLM Wiki for Ditto: How a Mac Mini Became My Second Brain Blog Building an LLM Wiki for Ditto: How a Mac Mini Became My Second Brain We Built a Browser Robot Because Webflow's API Can't Handle a Code BlockWe Built a Browser Robot Because Webflow's API Can't Handle a Code Block Blog We Built a Browser Robot Because Webflow's API Can't Handle a Code Block Build a Multiplayer Emoji Game in SwiftUI with Peer-to-Peer SyncBuild a Multiplayer Emoji Game in SwiftUI with Peer-to-Peer Sync Blog Build a Multiplayer Emoji Game in SwiftUI with Peer-to-Peer Sync Keep mission-critical systems online when it matters most Ditto is the only edge-native, mobile database that can consistently support your business anytime, anywhere. Edge-native solutions are built specifically to thrive on mobile and edge devices, without relying solely on cloud-based services. - Build flexible operations that are both latency-sensitive and resilient without reliance on network hardware, edge servers, or the cloud - Decentralize your systems to remove single points of failure that lead to operational bottlenecks - Drive consistent revenue and customer service anywhere, regardless of connectivity or bandwidth Try Ditto for FreeTry Ditto for Free Try Ditto for Free Meet with a Product SpecialistMeet with a Product Specialist Meet with a Product Specialist “When your POS goes down, that has a true financial cost to your business” Once Ditto is installed in your applications, write a few simple queries, and watch your mobile and edge devices automatically form mesh networks and share data directly without the need for servers or access points. Hear the full storyHear the full story Hear the full story See more customersSee more customers See more customers [The Ditto MongoDB Connector - Setup and Demo ](#) The Tech Take a quick look at the core technology powering our peer-to-peer and cloud sync plans. Foundational Technology Offline-first mobile database Even when devices are completely offline, they can always read, write, and process data Offline-first mobile database CRDT-powered conflict resolution To resolve concurrency conflicts that appear in decentralized models, as well as enable delta-based sync, Ditto harnesses the power of conflict-free replicated data type (CRDT) technology CRDT-powered conflict resolution [ P2P Sync ](#w-tabs-0-data-w-pane-0)[ Device Sync ](#w-tabs-0-data-w-pane-1) Automatic Device Discovery and Mesh Networking Devices running the same application automatically connect and maintain ad-hoc mesh networks without the need for manual pairing or configuration ![Automatic Device Discovery and Mesh Networking](https:\u002F\u002Fcdn.prod.website-files.com\u002F6761335affb7c1ca9aae00dd\u002F6797603559859902bdfdf85f_ditto_home-tech_visual_003@2x.webp) Direct Peer-to-Peer Sync Out-of-the-box support for BLE, P2P WiFi, LAN, and more enables real-time sync in disconnected or bandwidth-constrained environments Direct Peer-to-Peer Sync Opportunistic Cloud Sync Anytime internet is available to one or more devices within the mesh, all devices sync with your existing cloud systems Opportunistic Cloud Sync Opportunistic Cloud Sync Anytime internet is available, devices sync with your existing cloud systems Opportunistic Cloud Sync Success Stories See more customersSee more customers See more customers Vikram Baskaran “Our Ditto partnership is providing real-time visibility for inflight devices” \"Our approach to developing frontline tools prioritizes close partnership with our flight attendants during each development step. Ditto has been a great partner in ensuring our tools are seamless for our flight attendants. With their help, we have supported our workgroup by providing visibility of one another’s inflight mobile device… in real-time\" Read More Vikram BaskaranVP of IT Alaska Airlines Chris Taylor “Ditto moves key data quickly with no round trips to central services” “Ditto moves key operational data between retail team members quickly, seamlessly and with no round trips to central services. The more control and information we can put in the hands of operators and their teams, the better they can care for customers.” Read More Chris TaylorRetail Ops Manager Chick-fil-a Ms. Yu Abe “This technology truly revolutionizes the way crew members work” Ditto's remarkable capabilities enable smooth and stable communication among crew devices, even without connectivity during flight. This allows our crew to shift from former manual operations to a more advanced and efficient working style and enables us to create more room for the crew to introduce new services to passengers. This technology truly revolutionizes the way crew members work. Read More Ms. Yu AbeDirector, IT Planning & Promotion Department Japan Airlines Bryan Allebone “Ditto ensures USAF's data remains as reliably agile as we are” Ditto is our strategy to ensure that USAF's data remains as reliably agile as we are… with Ditto, married with these Apple Platforms… we can provide a seamless and mission-ready experience anywhere in the world, and under any circumstances. Read More Bryan AlleboneMajor 55th Wing \u002F BOCKSCAR U.S. Air Force Harness the full power of your existing mobile and edge infrastructure More WiFi isn’t the answer. Your mobile and edge devices are more powerful than you realize, capable of advanced networking without the need for new devices, hardware, or networking setups. Bridge connectivity gaps without added hardware or complexity. Once Ditto is installed in your applications, write a few simple queries, and watch your mobile and edge devices automatically form mesh networks and share data directly without the need for servers or access points. [ Swift ](#w-tabs-1-data-w-pane-0)[ KOTLIN ](#w-tabs-1-data-w-pane-1)[ JAVASCRIPT ](#w-tabs-1-data-w-pane-2)[ C# ](#w-tabs-1-data-w-pane-3)[ C++ ](#w-tabs-1-data-w-pane-4)[ RUST ](#w-tabs-1-data-w-pane-5) ```javascript \u002F\u002F initialize Ditto with your account credentials const ditto = new Ditto(...) ditto.startSync() \u002F\u002F insert data into your local data store await ditto.store.execute( \"INSERT INTO cars DOCUMENTS ({ 'color': 'blue' })\" ); \u002F\u002F listen for change to your local data store ditto.store.registerObserver(\"SELECT FROM cars\", (result) …. A Clean \u002F Minimalist, Typographic \u002F Big Type website in the SaaS & Software industry. 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This sophisticated design language positions the initiative not just as a government program, but as a pioneering frontier in human knowledge.","Technology & Hardware",[26,588,33],[],[],[],[859,861,863,865],{"score":860,"category":92},50,{"score":862,"category":95},99,{"score":864,"category":98},100,{"score":864,"category":101},[867,868,869,870],{"score":211,"category":92},{"score":862,"category":95},{"score":864,"category":98},{"score":864,"category":101},[111,119,115],"Website: Genesis Mission. Page: Homepage. Page type: Home \u002F Landing Page. Page title: Genesis Mission. Page description: A National Initiative to Accelerate Science Through AI. Genesis Mission is a national initiative to build the world's most powerful scientific platform to accelerate discovery science, strengthen national security, and drive energy innovation.. Page content: Fusion Fusion you can plug into Harnessing the power of the stars to deliver abundant, affordable energy. Through real-time collaboration between scientists, supercomputers, and AI systems, researchers can design, test, and stabilize fusion reactors far faster than before, accelerating the realization of sustainable fusion power.. A Dark Mode, Futuristic \u002F Sci-Fi, Typographic \u002F Big Type website in the Technology & Hardware industry. The overall color palette features Black, Gray, White. AI description: Genesis Mission serves as a high-stakes digital gateway for a national initiative aimed at revolutionizing scientific discovery through artificial intelligence. The platform is designed to communicate a sense of monumental purpose, bridging the gap between complex energy innovation, national security, and advanced computational science. It acts as a centralized hub for stakeholders, researchers, and the public to engage with the mission's progress and objectives. 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